Melatonin, also called the “sleep hormone ” is produced by the pineal gland at dusk. Melatonin thus plays a fundamental role in regulating our body clock as is responsible for the sleep / wake cycle. The pineal gland is sensitive to light and production of melatonin will reduce in the morning to onset awakening. Taken in excess of 1 mg, it helps reduce the time it takes to fall asleep.
Melatonin is widely know to help your body adjust to jet lag. When you travel through different time zone your pineal gland doesn’t adjust straight away to the new dusk “time”, delaying your onset of sleep. Tricking the body by giving it melatonin helps adapt to the new time zone until your body adjusts its circadian cycle.
Not only inducing sleep, melatonin is known to also improve the quality of your sleep during periods of stress. Indeed the overall of studies published since 2001 show it influence the time needed to fall asleep.
Melatonin works well to treat delayed sleep-phase disorder. This problem is related to a disturbance of the of the circadian rhythm. Sufferers fall asleep between 3 am to 6 am and wake up around mid-day to 3 pm.
Researchers have found that people with certain health problems had melatonin levels below average. They have also made a connection with the consumption of melatonin during the day that could help reduce some psychological stress-related disorders such as depression, anxiety and agitation. Researchers conducted a study taking into account stress as a major contributing factor to depression and demonstrating the importance of resynchronization of circadian rhythms for effective treatment of depression. This study highlighted the melatonin potential as an antidepressant.
Finally, it has also been shown to help people suffering from migraine, irritable bowel syndrome and fibromyalgia, as it can reduce chronic pain.
Consumption of melatonin is reasonable dose is relatively safe, however it should be used with caution and moderation and restricted to short term use. Prolonged use, could have some physiological side effect on your body’s natural production of melatonin. Your pineal gland could become lazy or stop its production if you substitute it with synthetic melatonin.
We’ve selected a range of supplements:
- Made of 100% natural active ingredients
- Completely bioavailable and biocompatible
- In “Controlled release” microgranules form to ensure prolonged effectiveness and targeted action in the body
Images Credit: DepositPhotos
Ballard CG, O’Brien JT, et al. Aromatherapy as a safe and effective treatment for the management of agitation in severe dementia: the results of a double-blind, placebo-controlled trial with Melissa.
Amsterdam JD1, Li Y, Soeller I, Rockwell K, Mao JJ, Shults J., A randomized, double-blind, placebo-controlled trial of oral Matricaria recutita (chamomile) extract therapy for generalized anxiety disorder. Depression Research Unit, University Science Center.
Hanus M1, Lafon J, Mathieu M, Double-blind, randomised, placebo-controlled study to evaluate the efficacy and safety of a fixed
combination containing two plant extracts (Crataegus oxyacantha and Eschscholtzia californica) and magnesium in mild-to-moderate anxiety disorders.
Étude sur l’Eschscholtzia californica menée par l’équipe du Laboratoire de Pharmacognosie de l’université de Metz .
9. Brzezinski A, Vangel MG, et al. Effects of exogenous melatonin on sleep: a meta-analysis. Sleep Med Rev. 2005 Feb;9(1):41-50.10. Buscemi N, Vandermeer B, et al. The efficacy and safety of exogenous melatonin for primary sleep disorders. A meta-analysis. J Gen Intern Med. 2005 Dec;20(12):1151-8.
42. Jansen S, Forbes D, Duncan V, Morgan D, Malouf R. Melatonin for the treatment of dementia.Cochrane Database Syst Rev. 2011;(1):CD003802. Résumé www2.cochrane.org
Detanico BC 1 , Piato AL , Freitas JJ , Lhullier FL , Hidalgo MP , Caumo W , Elisabetsky E .Antidepressant-like effects of melatonin in the mouse chronic mild stress model. Eur J Pharmacol 2009 1 avril; 607 (1-3): 121-5. doi: 10.1016 / j.ejphar.2009.02.037. Epub 2009 le 26 février.
35. The use of exogenous melatonin in delayed sleep phase disorder: a meta-analysis. van Geijlswijk IM, Korzilius HP, Smits MG. Sleep. 2010 Dec;33(12):1605-14.
12. Effect of melatonin administration on sleep, behavioral disorders and hypnotic drug discontinuation in the elderly: a randomized, double-blind, placebo-controlled study. Garzón C, Guerrero JM, et al. Aging Clin Exp Res. 2009 Feb;21(1):38-42.
Mcllwain H. Adenosine in neurohumoral · and regulatory roles in the brain. ln : Genazzani E, Herken H, eds. Central Nervous System – Studies on metabolic regulation and Junction. Berlin : Springer Verlag, 1973 : 3-11.
Harms HH, Wardeh G, Mulder AH. Effects of adenosine on depolarization induced release of various radiolabeled neurotransmitters from slices of rat corpus striatum. Neuroplw.muJCology 1979 ; 18 : 577-80.
Harms HH, Wardeh G, Mulder AH. Effects of adenosine on depolarization induced release of various radiolabeled neurotransmitters from slices of rat corpus striatum. Neuroplw.muJCology. 1979 ; 18 : 577-80.
Berne RM, Rubio R, Curnish RR. Release of adenosine from ischemie brain. Effect of cerebral vascular resistance and incorporation into cerebral adenine nucleotides. Circ Res 1974- ; 35 : 262-71.
Maitre M, Ciesielski L, Lehmann A, Kempf E, Mandel P. Protective effect of adenosine and nicotinamide against audiogenic seizure. Biochem Plw.muJCol 1974 ; 23 : 2807-16.
Jones P, Bachelard HS, Studies on amino acid metabolism in the brain using 15N-labeled precursors.
Your Vitality Store doesn’t intend to diagnose. Always assess your health requirements by seeing a professional medical practitioner.